Knowledgeable and Extensively Published
Greg is a well-known author of four books and many broadly-cited journal articles, including Bioconjugate Techniques a manual of bioconjugation chemistry and procedures, published by Elsevier (Academic Press), and now in its Third Edition (2013). In addition, Greg is the co-author of Immobilized Affinity Ligand Techniques, an overview of affinity chromatography methods published by Academic Press. He is also a member of ISI’s Highly Cited Researchers list with one publication in the top 50 of all time, including a total of over 27,000 citations to all publications.
Technical Consulting Services
Crosslinking or attachment of one molecule to another using a variety of reagents and reactions. Optimizing hydrophilicity, stability, and activity in the final conjugate.
Adding custom functionality or reactivity to a biomolecule to facilitate further reactions in the preparation of bioconjugates. Activation of proteins, thiolation, PEGylation, etc.
Modifying biomolecules with labels to create detectable conjugates for use in assays or imaging. Biotinylation, fluorescent dyes, fluorescent proteins, or enzyme labels.
ELISA and Fluorescent immunoassays for research or diagnostics. Improve sensitivity, reduce background, enhance reagent stability. Western blotting, single-plex, multiplex, or cell-based assays in many different formats.
Protein Expression & Purification
Enhance protein expression and stability. Develop affinity chromatography or classical methods of protein isolation. Use fusion tags, bioaffinity interactions, or immunoaffinity purifications.
Coupling of affinity molecules to solid phases to create affinity targeting or purification supports. Create array surfaces, microparticles, nanoparticles, and chromatography supports.
Immunogen and vaccine production using the latest carriers and conjugation techniques. New strategies to produce immunogens to modulate allergen reactions. Decrease antibody response to the carrier or crosslinker and maximize response to the hapten.
Conjugation with antibodies or antibody fragments through selected sites. Prepare better biotinylated or fluorescently labeled antibodies having enhanced stability and S/N. Options for preparing ADC conjugates or enzyme conjugates using a variety of antibody scaffolds.
Site Directed Coupling
Conjugation of biomolecules through discrete sites and functional groups to avoid active centers or binding regions. Form reproducible bioconjugates with maximal activity. Large library of reactions and reagents are available to use.
Business Consulting Services
GTH can review current draft agreements or aid in developing new ones. Confidentiality agreements (CDA), material transfer agreements (MTA), licensing or technology acquisition, collaborations and partnerships, or consulting agreements.
Add an experienced negotiator to your team to get the best deal possible. Over twenty-five years experience in technology acquisition and developing collaborative relationships.
With many years of experience, GTH can help in developing strategic plans designed to drive company growth. GTH works with your team to design the strategy and tactics that can increase revenues and result in a constant stream of new product development.
GTH can provide expert help in patent and prior art searching, aid in the preparation of patent applications, review intellectual property, and assess the valuation of IP. GTH works with patent agents or patent attorneys when necessary to bring in all the expert help you need.
GTH works with outside attorneys that can provide top level legal counsel in the bioscience fields. This includes intellectual property, contracts, and general counsel attorneys. GTH legal partners have extensive experience in the Life Science business areas.
Manufacturing and Quality
GTH has available expert leaders in the bioscience and biotech industries, who can aid in new product transfer from R&D, production scale-up, validation, and verification of your processes.
Experienced Help Anytime You Need It
Greg Hermanson, President
With over 35 years of experience working in the biotechnology and bioscience fields, Greg was directly responsible for millions of dollars in new technologies and products. You can now add this wealth of knowledge to your team to focus increased value into your business, R&D efforts, or manufacturing processes. Greg can quickly aid in solving problems in your development efforts through the combined strengths of experience and years of real world problem solving.